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Our Projects
1
Pancreatic cancer and the pro-metastatic liver niche
Studies aimed to define and target the pro-metastatic liver signals generated by chemotherapy that supports the survival and outgrowth of liver-resident disseminated tumor cells. Our major goal is to identify novel therapeutic approaches for reducing risk of disease recurrence.
2
Mammary epithelial plasticity and breast cancer progression
Our lab is working to define regulators of cell plasticity and cell fate-switching processes in injured mammary epithelial cells, in pre-invasive ductal carcinoma in situ, and in triple-negative breast cancer (TNBC). Our overall goal is to develop therapeutic strategies for intercepting drivers of aggressive disease, ultimately improving patient outcomes
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